Clomid (Clomiphene Citrate): Cost, Applications, Side Effects

Clomid, or clomiphene citrate, is a widely used medication for treating infertility in women. This detailed guide delves into various aspects of Clomid, such as its uses, dosages, side effects, precautions, and more.

What is Clomid?

Clomid (clomiphene citrate) is a non-steroidal fertility drug that induces the release of hormones necessary for ovulation. It is classified as a selective estrogen receptor modulator (SERM) and primarily prescribed to stimulate ovulation in women facing difficulties conceiving due to infrequent or absent ovulation.

Key Applications

Clomid is prescribed for several fertility-related issues in women, including:

  • Ovulatory dysfunction: Clomid is often the initial treatment for women experiencing infrequent or absent ovulation.
  • Polycystic ovary syndrome (PCOS): Clomid can be used in women with PCOS, a hormonal disorder that may result in irregular ovulation or anovulation.
  • Unexplained infertility: Clomid is sometimes combined with other fertility treatments for couples with unexplained infertility.

It is important to note that Clomid is not suitable for women with ovarian failure or primary pituitary failure, as it will not be effective in these cases.

Dosage and Usage Guidelines

Clomid comes in tablet form and is typically taken orally once daily for five consecutive days, starting on the third, fourth, or fifth day of the menstrual cycle. The standard starting dose is 50 mg per day, but your healthcare provider may adjust the dosage based on your individual response to the medication.

Cycle of Treatment Clomid Dosage
1st cycle 50 mg daily for five consecutive days
2nd cycle 100 mg daily for five consecutive days (if no ovulation occurs in the first cycle)
3rd cycle 150 mg daily for five consecutive days (if no ovulation occurs in the second cycle)

Your healthcare provider will closely monitor your response to Clomid through blood tests and ultrasound to determine the appropriate dosage and treatment duration. Always follow your healthcare provider’s instructions and avoid exceeding the recommended dosage or treatment duration.

Potential Side Effects of Clomid

While generally well-tolerated, Clomid may cause side effects. Common side effects include:

  • Hot flashes
  • Bloating
  • Abdominal discomfort
  • Breast tenderness
  • Headaches
  • Dizziness
  • Mood swings
  • Nausea

Less common but more severe side effects may include:

  • Ovarian hyperstimulation syndrome (OHSS): A potentially serious condition characterized by enlarged ovaries, abdominal pain, rapid weight gain, and difficulty breathing.
  • Visual disturbances: Temporary blurring or other visual disturbances may occur during or shortly after Clomid treatment.
  • Multiple pregnancies: Clomid increases the chances of multiple pregnancies (twins, triplets, etc.), which carry higher risks for both the mother and the babies.
  • Ovarian cysts: Clomid may cause the formation of ovarian cysts, which can lead to pain and discomfort.

If you experience severe or persistent side effects, contact your healthcare provider immediately.

Safety Measures and Drug Interactions

  • Have a history of thyroid or adrenal gland issues
  • Are pregnant or nursing
  • Are taking other medications, including over-the-counter drugs, vitamins, and supplements

Clomid might interact with other medications or supplements. It is crucial to inform your healthcare provider of all medications and supplements you are taking to prevent potential interactions.


Store Clomid at room temperature, away from heat, moisture, and direct light. Keep the medication out of reach of children and pets.

Cost of Clomid in the United States

Clomid prices in the United States may differ based on factors such as dosage form, strength, quantity, and the patient’s location. The following are estimated price ranges for oral Clomid tablets:

  • 50 mg tablets: $30-$60 for a package of 30 tablets
  • 100 mg tablets: $60-$90 for a package of 30 tablets

Please note that these prices are approximate and may not reflect the actual cost at your local pharmacy. Insurance coverage, pharmacy discounts, and generic versions may also significantly affect the final cost of Clomid.

Helpful Hints for Taking Clomid

  • Adhere to your healthcare provider’s guidelines for taking Clomid, and avoid exceeding the recommended dosage or treatment duration.
  • Monitor your menstrual cycle and any side effects you experience while using Clomid.
  • Attend all scheduled appointments with your healthcare provider to assess your response to Clomid treatment.
  • Adopt a healthy lifestyle, including a balanced diet, regular exercise, and stress management, to enhance your chances of successful pregnancy with Clomid treatment.
  • Engage in open communication with your healthcare provider and your partner about your fertility journey, expectations, and any concerns you may have.